The field of endodontics has seen significant developments since the first edition of this book was published in 2016. Evidence-based standards evolve as the literature changes, and practitioners must adapt their clinical practice accordingly. The second edition of this study guide—known in some circles as “The Orange Book”—has been updated based on new peer-reviewed journal articles, position statements, and guidelines, and revisions are reflected in the current treatment protocols for pulpal and periapical diseases as well as traumatic dental injuries, cracked and fractured teeth, and resorptive dental injuries. Each chapter concludes with an extensive bibliography of the scientific literature for further reference. Whether this book is supplementing your predoctoral or postdoctoral endodontics curriculum or guiding your self-study in general dental or specialty practice, know you will be at the forefront of the field.